Shyamaji Krishnavarma first came to Britain in 1879 as a Sanskrit scholar and assistant to Professor Monier Williams at Oxford. He graduated from Balliol College in 1883 and was called to the Bar in 1884. In 1881, he attended the Berlin Congress of Orientalists.

Krishnavarma returned to India to work in service to the Indian Princely States and then returned to England in 1897, settling with his wife at Highgate. They first lived at a house he bought at 9 Queenswood Avenue. He endowed an annual lecture in honour of Herbert Spencer in 1904, after attending the funeral service of Herbert Spencer in Golders Green in December 1903. He also created scholarships for Indian students to study in Britain from 1905, on the condition that they would not work for the British Government.

In February 1905, Krishnavarma founded the Indian Home Rule Society. He then established India House in Highgate (at 65 Cromwell Avenue) in the same year (July 1905), as a hostel for Indian students, which became a meeting-place for Indian revolutionaries in London. Krishnavarma fled to Paris in 1907 to avoid arrest and censure by the British Government in relation to his published inflammatory material, such as the journal The Indian Sociologist, and the political activities of India House. He was also disbarred from Inner Temple. After a lapse between 1914 and 1920, Krishnavarma began to publish The Indian Sociologist again from Geneva until 1922. He died in Geneva in 1930.